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Table 1 Experimental groups.*

From: Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model

Groups Infection (P. aeruginosa) Intervention n
Control None   3
Co-instillation Antibodies were premixed with PA103
   Control IgG PA103 (5 × 107 CFU), IT Control IgG (IgG2b), 4 mg/ml IT 3
   Rab anti-PcrV PA103 (5 × 107 CFU), IT Polyclonal anti-PcrV IgG, 4 mg/ml IT 3
   Mab166 PA103 (5 × 107 CFU), IT Monoclonal Mab166, 4 mg/ml IT 3
Therapeutic Antibodies were intratracehally instilled 1 h after the instillation of PA103
   w/o IgG PA103 (5 × 107 CFU), IT Phosphate-buffered saline 5
   Rab anti-PcrV PA103 (5 × 107 CFU), IT Polyclonal anti-PcrV IgG, 4 mg/ml IT 3
   Mab166 PA103 (5 × 107 CFU), IT Monoclonal Mab166, 4 mg/ml IT 5
   Mab166 Fab PA103 (5 × 107 CFU), IT Fab fragments of Mab166, 4 mg/ml IT 3
  1. *IT: Intratracheal administration