Figure 3
From: Dendritic cells: In the forefront of immunopathogenesis and vaccine development – A review
Induction of primary immune responses by DCs. The DC lineage comprises cells at different stages of differentiation and development in different tissues. The currently accepted scheme suggests that DCs from bone marrow move via the blood into non-lymphoid tissues. In these organs they undergo different changes with respect to shape, functions. In these organs DCs induce primary T cell immune responses.