Figure 5
From: Dendritic cells: In the forefront of immunopathogenesis and vaccine development – A review
Transdermal delivery of immunogenic fusion protein by cutaneous DCs. Genetically engineered immunogenic fusion protein can be transdermaly administrated into the skin whereby cutaneous DC subsets can capture it via DC-peptide motifs fused to immunogen subunits. Loaded cutaneous DC subsets can be activated, leave the skin and enter the lymph nodes where they can present processed antigen as immunogenic peptides to T cells eliciting specific T cell immune responses.