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Figure 4 | Journal of Immune Based Therapies and Vaccines

Figure 4

From: Human anti-anthrax protective antigen neutralizing monoclonal antibodies derived from donors vaccinated with anthrax vaccine adsorbed

Figure 4

Determination of AVP-21D9 IC 50 using RAW 264.7 264.7 cell based assay 1.2 nM PA and 0.56 nM LF in a 96 well assay on confluent RAW 264.7 264.7 cells cause 100% cell lysis. The AVP-21D9 was assessed at various concentrations for the ability to inhibit the lethal toxin. From the dose response curve an IC50 values was estimated. AVP-22G12 and AVP-1C6 IC50 determinations were carried out likewise.

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Journal of Immune Based Therapies and Vaccines

ISSN: 1476-8518