Table 2 Fold difference in geometric mean titers of VLP+MAA-immunized group over VLP alone-immunized group.
A. | HPV cLIA time (weeks) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
HPV type | 0 | 2 | 4 | 8 | 10 | 12 | 16 | 20 | 24 | 26 | 28 | 52 |
HPV 6 | 1.1 | 3.2 | 2.4 | 4.3 | 10.0 | 12.6 | 36.3 | 10.9 | 6.3 | 22.7 | 41.9 | 4.3 |
HPV 11 | 0.8 | 2.9 | 2.2 | 5.5 | 23.5 | 18.1 | 16.2 | 8.2 | 6.1 | 18.4 | 36.8 | 5.3 |
HPV 16 | 1.0 | 5.2 | 8.8 | 8.4 | 21.4 | 15.7 | 16.1 | 11.4 | 17.7 | 4.8 | 12.7 | 6.4 |
HPV 18 | 1.0 | 4.8 | 13.7 | 19.4 | 70.5 | 18.6 | 27.1 | 35.4 | 26.3 | 6.7 | 26.8 | 26.7 |
B. | HPV Total IgG antibodies time (weeks) | |||||||||||
HPV type | 0 | 2 | 4 | 8 | 10 | 12 | 16 | 20 | 24 | 26 | 28 | 52 |
HPV 6 | 1.9 | 9.5 | 9.5 | 13.1 | 125.0 | 328.3 | 125.0 | 65.7 | 34.4 | 34.5 | 65.7 | 18.1 |
HPV 11 | 1.9 | 13.1 | 25.0 | 25.0 | 125.0 | 90.6 | 125.0 | 47.6 | 34.5 | 34.5 | 90.6 | 18.1 |
HPV 16 | 0.9 | 5.0 | 9.5 | 6.9 | 65.7 | 65.7 | 90.6 | 65.7 | 13.1 | 13.1 | 65.7 | 25.0 |
HPV 18 | 0.7 | 9.5 | 13.1 | 25.0 | 125.0 | 47.6 | 65.7 | 65.7 | 25.0 | 47.6 | 125.0 | 90.6 |