| |
CD4
|
CD8
| |
|---|
| |
IRIS
|
p value
|
|---|
|
HLA-DR
|
27.4 (16–38.4)
|
28.7 (24.6–32)
|
< 0.005/n.s
|
|
CD38
|
77 (70–78.5)
|
82.6 (75.3–90.7)
|
n.s/< 0.05
|
|
CD38 MFI
|
1118 (1253-780)
|
493 (548-297)
|
< 0.02/< 0.01
|
|
Naïve
|
19.4 (6.9–23.9)
|
25 (7–42)
|
< 0.005/n.s
|
|
Memory
|
85 (44–96)
|
53.8 (37.5–76)
|
n.s/n.s
|
| |
CP
| |
|
HLA-DR
|
7.3 (5.4–9.2)
|
30.5 (22–40)
| |
|
CD38
|
66 (60.7–71.7)
|
73 (61.7–80)
| |
|
CD38 MFI
|
173 (85–211)
|
133 (105–146)
| |
|
Naïve
|
35 (30–45)
|
32 (24.6–42)
| |
|
Memory
|
59 (54–67)
|
38 (26–46)
| |
| |
UC
| |
|
HLA-DR
|
4 (2.8–5.3)
|
7.6 (6.9–9.9)
| |
|
CD38
|
70 (68–75.5)
|
66 (66–70)
| |
|
CD38 MFI
|
97 (71–116)
|
85 (58–87)
| |
|
Naïve
|
40.8 (40–49)
|
60.4 (51.2–61.5)
| |
|
Memory
|
30 (29.2–40)
|
22 (20.8–30.3)
| |
- IRIS- Immune reconstitution inflammatory syndrome patients; CP- asymptomatic clinical progressors; UC- uninfected controls. Data are shown as median percentage, and CD38 mean fluorescent intensity (MFI) (interquartile range). p values shown between IRIS and CP patients for CD4/CD8 data respectively.
