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Table 1 The combined potency loss rate estimates of VZV (Oka/Merck) in both, hydrolyzed porcine gelatin (SOL-U-PRO), as well as recombinant human gelatin (FG-5001) stabilized, experimental refrigerator-stable varicella vaccine formulations stored at -15°C and 2–8°C for 24 months, and at 15°C for 12 months, respectively. The potency loss rates are in log10 PFU per month.

From: Evaluation of a recombinant human gelatin as a substitute for a hydrolyzed porcine gelatin in a refrigerator-stable Oka/Merck live varicella vaccine

  Potency Loss Rate Estimates (95%CI)
Storage Temperature SOL-U-PRO FG-5001 Combined
-15°C 0.000 (-0.004,0.005) 0.000 (0.005, 0.005) 0.000 (-0.003, 0.004)
2–8°C 0.005 (0.000, 0.010) 0.005 (0.000, 0.010) 0.005 (0.001, 0.009)
15°C 0.033 (0.017, 0.049) 0.033 (0.017, 0.048) 0.033 (0.022, 0.044)
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