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Figure 2 | Journal of Immune Based Therapies and Vaccines

Figure 2

From: CTLA-4 blockade during dendritic cell based booster vaccination influences dendritic cell survival and CTL expansion

Figure 2

LCMV gp3333–41 specific CTL levels are stable during repetitive DC vaccination. C57/Bl6 mice were immunized with peptide LCMV gp3333–41 loaded DCs day -14 and -7 in combination with i.p. injection of anti-CTLA-4 mAb. Spleen cells from individual mice were isolated day 0, cocultured with LCMV gp3333–41 peptide for 7–10 days and tested for reactivity against the peptide in an IFN-γ ELISPOT assay. Results are shown as mean ± SD of eight mice from two separate experiments. (* p < 0.05)

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