Figure 4

Proliferative responses in PBMC from healthy (open circles, n = 10 to 12) or HCV-infected (filled circles, n = 10 to 15) donors after incubation with A-, B- or C-Class CpG (6 μg/ml), positive control PHA (10 μg/ml) or non-CpG control ODN (6 μg/ml) for 5 days, then pulsing with 3H-thymidine for 16 to 18 hours. Horizontal bars represent the group means for stimulation indices (SI = cpm with PHA or ODN/cpm with media alone).