Figure 6

Percent change in amount of IFN-α secreted by PBMC after 48 hr culture with rIFN-α (125 IU/ml) plus C-Class CpG (6 μg/ml) over that with CpG alone. The amount of IFN-α measured for rIFN-α alone for each subject was subtracted from the rIFN-α plus CpG value to account for rIFN-α itself remaining in the culture media. Individual data is shown for PBMC from healthy (open bars, n = 12) or HCV-infected (closed bars, n = 15) donors.