Figure 4

Change in CD4⁺ T and mast cells during acute cystitis. Control or anti-mouse CXCL10 Ab solutions were administered 2 days prior to CYP treatment and every 2 days thereafter. Five days after CYP administration, lymphocytes from the spleen, iliac lymph nodes, and urinary bladder were isolated and stained for flow cytometry analysis. Representative histograms are shown with the mean percentage (and total number) of spleen, iliac lymph node, and urinary bladder CD4⁺ T cells (Panel A), CD34⁺ cKit⁺cell (Panel B).