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Table 4 Immune response gene profile of splenocytes after 5 h immunization with E. coli vaccine.

From: Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella

  Gene Fold Regulationa   Gene Fold Regulation
Th1 Regulation Csf2 2.07 Th2 Regulation Genes Il10 1.37
  Ifna4 5.10   Il13 3.14
  Ifng 1.11   Il1f5 -10.20
  Il12b 2.38   Il4 1.04
  Il16 6.73   Il9 9.25
  Il18 -1.04    
  Il2 1.27 Other Immune Response Genes Ifnb1 -3.36
  Il27 -1.11   Il1f10 6.73
  Tnf 3.14   Il1rn 4.44
  Tnfsf15 11.71   Il21 6.28
  Tnfsf4 5.10   Tnfsf8 10.93
  Cd40lg 4.44   Tnfsf9 6.28
  1. aValues are real-time PCR expression of recombinant invasive E. coli vaccinated animals relative to expression of non-invasive E. coli vaccinated animals. Data were compiled from triplicate wells. T-test p value < 0.001.