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Table 4 Immune response gene profile of splenocytes after 5 h immunization with E. coli vaccine.

From: Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella

 

Gene

Fold Regulationa

 

Gene

Fold Regulation

Th1 Regulation

Csf2

2.07

Th2 Regulation Genes

Il10

1.37

 

Ifna4

5.10

 

Il13

3.14

 

Ifng

1.11

 

Il1f5

-10.20

 

Il12b

2.38

 

Il4

1.04

 

Il16

6.73

 

Il9

9.25

 

Il18

-1.04

   
 

Il2

1.27

Other Immune Response Genes

Ifnb1

-3.36

 

Il27

-1.11

 

Il1f10

6.73

 

Tnf

3.14

 

Il1rn

4.44

 

Tnfsf15

11.71

 

Il21

6.28

 

Tnfsf4

5.10

 

Tnfsf8

10.93

 

Cd40lg

4.44

 

Tnfsf9

6.28

  1. aValues are real-time PCR expression of recombinant invasive E. coli vaccinated animals relative to expression of non-invasive E. coli vaccinated animals. Data were compiled from triplicate wells. T-test p value < 0.001.