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Table 5 Three day cytokine production (pg/ml)a of vaccinated mouse splenic T cells cultured in macrophages with (+) or without (-) 50 μM GFP peptide HYLSTQSAL.

From: Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella

Vaccine Group Th1 Cytokines Th2 Cytokines
  TNFα IFNγ IL2 IL4 IL5
  (-) (+) (-) (+) (-) (+) (-) (+) (-) (+)
GFP 43.3 179.1 421.6 520.8 0 24 3.2 5.2 51.9 41.5
GFPinv 90.7 348.8 628.9 1353.7 1.9 32.2 4.0 3.8 56.2 10.2
GFPinvIL12 79.5 443.7 349.3 1307.2 22.3 36.7 3.2 0 17.9 5.8
()invIL12 110.8 147.5 673.6 862.9 24.8 3.1 3.0 5.9 71.1 41.4
RAW/GFP 134.7 566.2 NAb NA 10.4 24.8 11.6 0 14.4 0
PBS 127.2 84.5 130.0 440.0 2.2 3 0 12 0 14.1
  1. aValues are from pooled T cells from four mice of each vaccine group. Data are compiled from two experiments. A significant change in expression is indicated by 2-fold or greater over non-peptide treated samples (p < 0.05) and is shown in bold text. Decreases are in italics.
  2. bNot enough cells to perform assay.