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Figure 3 | Journal of Immune Based Therapies and Vaccines

Figure 3

From: Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B

Figure 3

Assessment of HuMAbs in vitro neutralization activity against SEB. A) Dose-dependent cytokine production inhibitory activity of HuMAb-79G9 as compared to an irrelevant IgG1κ. Each bar represents the average of triplicate samples ± the SD and the data shown are representative of two or more independent experiments. At all antibody concentrations for each cytokine, % inhibition by HuMAb-79G9 was significant (P < 0.05) as compared to % inhibition by an irrelevant hIgG. B) Comparison of dose-dependent cytokine production inhibitory activity of three lead HuMAbs. Each point on each line represents the average of triplicate samples ± the SD and the data shown are representative of two or more independent experiments.

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