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Table 1 Bacterial load in terms of CFU in lung and spleen of infected animals after immunotherapy and short-term chemotherapy

From: Immunotherapeutic role of Ag85B as an adjunct to antituberculous chemotherapy

Groups No. of CFU(× 105) in
  Lung ± 95% CI P value Spleen ± 95% CI P value
Basal 2.66 ± 0.254 0.22 (5.20-5.64)   1.22 ± 0.616 0.54 (4.54-5.62)  
Untreated 83.72 ± 0.527 0.46 (6.46-7.38)   12.5 ± 0.707 0.62 (5.47-6.71)  
ATD dialy 0.196 ± 0.814 0.71 (3.58-5.00) 0.0003 * 0.080 ± 0.509 0.45 (3.45-4.35) 0.0005 *
IT 0.507 ± 0.639 0.56 (4.14-5.26) 0.0003 * 0.061 ± 0.47 0.41 (3.37-4.19) 0.0003 *
ATD dialy+ IT(o/w) 0.086 ± 0.523 0.46 (3.47-4.39) 0.0001 * 0.029 ± 0.448 0.39 (3.07-3.85) 0.0001 *
ATD(o/w) +IT (o/w) 0.435 ± 0.978 0.86 (3.77-5.49) 0.0017 * 0.114 ± 0.667 0.58 (3.47-4.63) 0.0016 *
Untreated (2 months) 147 ± 0.551 0.48 (6.68-7.64)   15.6 ± 0.028 0.02 (6.17-6.21)  
ATD dialy 1 month + 1 month adjuvant immunized 1.29 ± 0.315 0.28 (4.83-5.39)   2.70 ± 0.99 0.87 (4.56-6.3)  
ATD dialy (1 month) + IT next month (o/w) 0.31 ± 0.319 0.28 (4.21-4.77) 0.0001 $
0.014 #
0.088 ± 0.44 0.39 (3.55-4.33) 0.0001 $
0.015 #
  1. * With respect to Untreated
  2. $ With respect to group Untreated (2 months)
  3. # With respect to group ATD daily 1 month + 1 month adjuvant immunized
  4. CFU: colony Forming Units; ATD: Anti Tuberculous Drugs; IT: Immunotherapy; o/w: Once Weekly;
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