Figure 4

Statistical analysis of DC differentiation markers. The expression of markers of DC differentiation were compiled from the overnight culture of DC induced by column passage with and without apoptotic cell loading that had been obtained from 7 CTCL patients, averaged and analyzed for significance in comparison to the values obtained on primary isolation. a: Mean fluorescence intensity (MFI) of class II expression on Day 0, primary isolation (Pre Tx; pre-treatment), or Day 1 column activated cells loaded with apoptotic CTCL or co-cultivated in the presence of viable CTCL cells (Mann-Whitney Rank Sum Test). b: Percent of monocytes expressing CD86 on primary isolation, or after column activation and overnight culture with and without apoptotic cell ingestion (t test). c: Percent of monocytes expressing cytoplasmic CD83 on primary isolation or after column activation and overnight cultivation with and without apoptotic cell up-take (Mann-Whitney Rank Sum Test).