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Journal of Immune Based Therapies and Vaccines

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  1. Content type: Review

    Mycobacterium avium subsp. paratuberculosis (MAP) infection causes in ruminants a regional chronic enteritis that is increasingly being recognized as a significant problem affecting animal health, farming and the...

    Authors: Felix Bastida and Ramon A Juste

    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:8

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  2. Content type: Original research

    The prognosis of patients with advanced non small cell lung (NSCLC) cancer remains dismal. Epidermal Growth Factor Receptor is over-expressed in many epithelial derived tumors and its role in the development a...

    Authors: Pedro C Rodriguez, Elia Neninger, Beatriz García, Xitlally Popa, Carmen Viada, Patricia Luaces, Gisela González, Agustin Lage, Enrique Montero and Tania Crombet

    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:7

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  3. Content type: Short report

    The induction of sterile immunity and long lasting protection against malaria has been effectively achieved by immunization with sporozoites attenuated by gamma-irradiation or through deletion of genes. For mi...

    Authors: Bruno Douradinha, Melissa van Dijk, Geert-Jan van Gemert, Shahid M Khan, Chris J Janse, Andy P Waters, Robert W Sauerwein, Adrian JF Luty, Bruno Silva-Santos, Maria M Mota and Sabrina Epiphanio

    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:6

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  4. Content type: Original research

    Streptococcus pneumoniae causes widespread morbidity and mortality. Current vaccines contain free polysaccharides or protein-polysaccharide conjugates, and do not induce protection against serotypes that are not ...

    Authors: Harm HogenEsch, Anisa Dunham, Bethany Hansen, Kathleen Anderson, Jean-Francois Maisonneuve and Stanley L Hem

    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:5

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  5. Content type: Original research

    Placebo-controlled, randomized, phase 2b trial was conducted in 34 adults comprising 18 first-diagnosed (52.9%), 6 relapsed (17.6%), and 10 MDR-TB (29.4%) cases to investigate the safety and efficacy of an ora...

    Authors: Dmitry A Butov, Yuri N Pashkov, Anna L Stepanenko, Aleksandra I Choporova, Tanya S Butova, Dendev Batdelger, Vichai Jirathitikal, Aldar S Bourinbaiar and Svetlana I Zaitzeva

    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:3

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  6. Content type: Short report

    We have evaluated an attenuated Listeria monocytogenes (Lm) candidate vaccine vector in nonhuman primates using a delivery regimen relying solely on oral vaccination. We sought to determine the impact of prior Lm...

    Authors: James B Whitney, Saied Mirshahidi, So-Yon Lim, Lauren Goins, Chris C Ibegbu, Daniel C Anderson, Richard B Raybourne, Fred R Frankel, Judy Lieberman and Ruth M Ruprecht

    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:2

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  7. Content type: Original research

    Staphylococcal enterotoxins are considered potential biowarfare agents that can be spread through ingestion or inhalation. Staphylococcal enterotoxin B (SEB) is a widely studied superantigen that can directly ...

    Authors: Brian Drozdowski, Yuhong Zhou, Brad Kline, Jared Spidel, Yin Yin Chan, Earl Albone, Howard Turchin, Qimin Chao, Marianne Henry, Jacqueline Balogach, Eric Routhier, Sina Bavari, Nicholas C Nicolaides, Philip M Sass and Luigi Grasso

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:9

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  8. Content type: Original research

    Dendritic cells (DCs) play a key role in innate and adaptive immunity but the access to sufficient amount of DCs for basic and translational research has been limited.

    Authors: Shuhong Han, Yichen Wang, Bei Wang, Ekta Patel, Starlyn Okada, Li-Jun Yang, Jan S Moreb and Lung-Ji Chang

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:8

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  9. Content type: Short report

    Several approaches have been explored to eradicate HIV; however, a multigene vaccine appears to be the best option, given their proven potential to elicit broad, effective responses in animal models. The Pr55Gag ...

    Authors: Sirika Pillay, Enid G Shephard, Ann E Meyers, Anna-Lise Williamson and Edward P Rybicki

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:7

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  10. Content type: Original research

    We previously demonstrated that polyphosphazenes, particularly PCEP, enhance immune responses in mice immunized subcutaneously and intranasally. The objective of the present study was to investigate the effica...

    Authors: Nelson F Eng, Srinivas Garlapati, Volker Gerdts, Lorne A Babiuk and George K Mutwiri

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:4

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  11. Content type: Original research

    Tuberculosis (TB) is one of the most prevalent cause of death due to a single pathogen. Bacillus Calmette Guérin (BCG) is the only vaccine available for clinical use that protects against miliary TB; however, ...

    Authors: Rajpal S Kashyap, Aliabbas A Husain, Shweta H Morey, Milind S Panchbhai, Poonam S Deshpande, Hemant J Purohit, Girdhar M Taori and Hatim F Daginawala

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:3

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  12. Content type: Short report

    Studies have shown that CpG oligodeoxyribonucleotides (ODN) protect mice from various bacterial pathogens, including Burkholderia pseudomallei and Francisella tularensis live vaccine strain (LVS), when administer...

    Authors: David A Rozak, Herbert C Gelhaus, Mark Smith, Mojgan Zadeh, Louis Huzella, David Waag and Jeffrey J Adamovicz

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:2

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  13. Content type: Short report

    Active vaccination can be effective as a post-exposure prophylaxis, but the rapidity of the immune response induced, relative to the incubation time of the pathogen, is critical. We show here that CD40mAb conj...

    Authors: Vijay NS Bhagawati-Prasad, Evy De Leenheer, Nadine P Keefe, Lorna A Ryan, Jennifer Carlring and Andrew W Heath

    Citation: Journal of Immune Based Therapies and Vaccines 2010 8:1

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  14. Content type: Original research

    Conserved neutralizing epitopes are considered to be a key role for eliciting broadly neutralizing antibody (NAb). Previously, two conserved neutralizing epitopes of HIV-1 CRF01_AE envelope were identified at ...

    Authors: Apichai Sreepian, Jongruk Permmongkol, Wannee Kantakamalakul, Sontana Siritantikorn, Nattaya Tanlieng and Ruengpung Sutthent

    Citation: Journal of Immune Based Therapies and Vaccines 2009 7:5

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  15. Content type: Original research

    Our group previously demonstrated that a DNA plasmid encoding the mycobacterial 65-kDa heat shock protein (DNA-HSP65) displayed prophylactic and therapeutic effect in a mice model for tuberculosis. This protec...

    Authors: Rubens R Santos, Alexandrina Sartori, Deison S Lima, Patrícia RM Souza, Arlete AM Coelho-Castelo, Vânia LD Bonato and Célio L Silva

    Citation: Journal of Immune Based Therapies and Vaccines 2009 7:4

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  16. Content type: Commentary

    Influenza viruses pose a permanent threat to human populations due to their ability to constantly adapt to impact immunologically susceptible individuals in the forms of epidemic and pandemics through antigeni...

    Authors: Carlos Franco-Paredes, Peter Carrasco and Jose Ignacio Santos Preciado

    Citation: Journal of Immune Based Therapies and Vaccines 2009 7:2

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  17. Content type: Original research

    There is no safe, effective human vaccine against brucellosis. Live attenuated Brucella strains are widely used to vaccinate animals. However these live Brucella vaccines can cause disease and are unsafe for huma...

    Authors: Jerome S Harms, Marina A Durward, Diogo M Magnani and Gary A Splitter

    Citation: Journal of Immune Based Therapies and Vaccines 2009 7:1

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  18. Content type: Original research

    Efficacious immune-based therapy in treated chronic HIV-1 infection requires the induction of virus-specific CD4+ T cells and subsequent maturation and maintenance of specific memory CD8+ T cells. Concomitant dai...

    Authors: Anna A Herasimtschuk, Samantha J Westrop, Graeme J Moyle, Jocelyn S Downey and Nesrina Imami

    Citation: Journal of Immune Based Therapies and Vaccines 2008 6:7

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  19. Content type: Original research

    The gram-positive bacterium Streptococcus pyogenes is a common pathogen of humans that causes invasive infections, toxic-shock syndrome, rheumatic fever, necrotizing fasciitis and other diseases. Detection of ant...

    Authors: Robert G Ulrich

    Citation: Journal of Immune Based Therapies and Vaccines 2008 6:8

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  20. Content type: Original research

    Alterations in serum CXCR3 ligand levels were examined in interstitial cystitis (IC) patients; similar expression patterns in serum as well as CXCR3, CXCR3 ligands, and cytokines expressed by peripheral and lo...

    Authors: Senthilkumar K Sakthivel, Udai P Singh, Shailesh Singh, Dennis D Taub, Kristian R Novakovic and James W Lillard Jr

    Citation: Journal of Immune Based Therapies and Vaccines 2008 6:6

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