Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses

Table 2 Average weights and cell numbers of spleens from mice treated with different adjuvants.

Mouse Group	Spleen Weight (mg)	Cell Numbers/Spleen (× 10⁷)
Mouse injected with PBS	90.2 ± 5.6	6.5 ± 1.2
Mouse injected with Pristane	110.5 ± 6.4	7.6 ± 0.9
Mouse injected with IFA	160.3 ± 1.3	8.3 ± 0.5
Mouse injected with CFA	642.3 ± 2.4	35.6 ± 2.3
Mouse injected with Phytol (80 μg)	665.6 ± 5.7	42.4 ± 2.2
Mouse injected with PHIS-01 (80 μg)	141.3 ± 3.2	8.1 ± 1.2

All data are expressed as mean ± SD (n = 3 per group in two separate experiments).